2005–2026
193 entries· 64 essays· the site as data →
Aneesh Sathe

Aneesh Sathe

I work at the intersection of AI, data science, and biomedical R&D — mostly on systems that help scientists turn messy biological and clinical data into clearer decisions.

Currently VP of AI & Data Science at Qureator; before that I co-founded Qritive, an AI pathology company. I write with the Protocol Institute on World Machines.

This site is where I write about technology, books, leadership, music, family, startups, and whatever else I'm trying to understand.

AI explorations and experiments, from studio.aneeshsathe.com.

  • How to Implement AI for Scientific R&D

    When scientists think of AI, the chances are they imagine either a chatbot or some undefined thing that combines all their data and gives insight. …

  • Neurosymbolic AI for Private Email Triage

    Safety note. I am intentionally not publishing the complete automation code in this post. An email-processing agent can expose private correspondence or take …

  • Causal Analysis for Biologists – Introduction

    Over a decade ago I created a rogue teaching course called Data Analysis for Biologists. At that time most biologists were untrained and afraid of any kind of …

  • Causality Belongs in Your Biotech From Day One

    Every decision in your biotech startup is based on a causal claim: “The compound works.” “The assay predicts efficacy.” “We should run the bigger study.” …

  • Auto Creating Knowledge Graphs from PDF files using LLMs

    Using systems like RAG and Knowledge graphs to serve as a source of truth for LLMs is extremely powerful. However, the creation of knowledge graphs themselves …

Short notes and microblog posts.

  • Learned about Omarchy… I’m glad I don’t have a test computer lying around. I’m worried I might get one.

  • Reply to: https://substack.com/profile/40247471-andre/note/c-320822257 APIs are already polite ways to interact with other programmers, I don’t see why that should be reinvented. My interactions are …

  • I was thinking about how, in Marathi, you don’t really need to say please and thank you constantly. You can walk into a shop, ask for something, pay, and leave without even a “bye” or “have a good …

  • Over on the Protocol Insitute chat rafa. asked how one would give a robot a personality. My opinion is you don’t: Does a robot need to be given a personality or is personality something we use as a …

  • Sing and Sing 2 are wonderful movies. Don’t know how I missed them for so long 🐨

Longer, more developed essays.

  • 2 Aug 2026
    Nakatomi DriftWorld Machines

    How to Get Properly Lost

    15 min read
  • 1 Aug 2026
    Blaugust Begins

    A few weeks ago I decided it was time to firmly exit the platforms. At first I was going to do some kind of cross-posting but most don’t have an exposed API or …

    2 min read
  • 29 Jul 2026
    Masks in Redshift

    On the masks that helped me navigate repeated moves and reinventions—and the freedom of no longer needing them.

    3 min read
  • 21 Jul 2026
    On Thickets, Enclosure, and LeavingWorld Machines

    Back to Liveness

    8 min read
  • 19 Jul 2026
    The Birth of ThicketsWorld Machines

    An Interregnum in Space

    11 min read

Essays in the World Machines collection.

  • 2 Aug 2026
    Nakatomi Drift

    How to Get Properly Lost

  • 21 Jul 2026
    On Thickets, Enclosure, and Leaving

    Back to Liveness

  • 19 Jul 2026
    The Birth of Thickets

    An Interregnum in Space

  • 12 May 2026
    Not My Lever

    The Last Container

Links out, with commentary.

  • 22 Aug 2026
    Delete Everything, Keep Graph -Karpathy youtube.com

    Bookmarked: Delete Everything, Keep Graph -Karpathy

  • 21 Aug 2026
    Bonsai reconstructs tree representations for distortion-free visualization and exploration of high-dimensional data - Nature Biotechnology nature.com

    Bookmarked: Bonsai reconstructs tree representations for distortion-free visualization and exploration of high-dimensional data - Nature Biotechnology I wonder …

  • 21 Aug 2026
    22nd Century Indian Documentary youtube.com

    Bookmarked: 22nd Century Indian Documentary

  • 21 Aug 2026
    Understanding is the new bottleneck geoffreylitt.com

    Bookmarked: Understanding is the new bottleneck

  • 21 Aug 2026
    Online version of The Remix is now here causalinf.substack.com

    Bookmarked: Online version of The Remix is now here Always here to share good books on causality and Bayesian stats