2005–2026
121 entries· 61 essays· the site as data →
Aneesh Sathe

Aneesh Sathe

I work at the intersection of AI, data science, and biomedical R&D — mostly on systems that help scientists turn messy biological and clinical data into clearer decisions.

Currently VP of AI & Data Science at Qureator; before that I co-founded Qritive, an AI pathology company. I write with the Protocol Institute on World Machines.

This site is where I write about technology, books, leadership, music, family, startups, and whatever else I'm trying to understand.

Short notes and microblog posts.

  • When exploring a new Space, especially with friends, your job is not just to keep exploring at high level. Sometimes you need to become a Place. When you find some little nugget that attracts your …

  • The new Opus model was released. It is supposed to be less susceptible to prompt injection.

  • Coppicing, not pruning. You cut back hard precisely so the roots keep their vigor and the next growth comes up faster. A blog wants the same maintenance: trim on a whim, never lose the roots.

  • Long grass at ground level this morning. Below the resolution of the map: blades crossing at every angle, no dominant direction. That is the understory feeling I keep chasing in the writing.

  • Walked out the side door of another platform today. Not with a manifesto, just a quiet exit into the rest of the internet, which is, it turns out, still infinite.

Longer, more developed essays.

  • 21 Jul 2026
    On Thickets, Enclosure, and LeavingWorld Machines

    Back to Liveness

    8 min read
  • 19 Jul 2026
    The Birth of ThicketsWorld Machines

    An Interregnum in Space

    11 min read
  • 3 Jul 2026
    The Ocean

    Wound up at the beach today. A proper San Diego beach. Unlike Carlsbad beaches, San Diego beaches tend to be a bit cropped but they are always livelier. This …

    2 min read
  • 12 May 2026
    Not My LeverWorld Machines

    The Last Container

    12 min read
  • 25 Apr 2026
    The Lightening of IntentWorld Machines

    Why Execution Got Cheap and Intent Got Live

    16 min read

Essays in the World Machines collection.

  • 21 Jul 2026
    On Thickets, Enclosure, and Leaving

    Back to Liveness

  • 19 Jul 2026
    The Birth of Thickets

    An Interregnum in Space

  • 12 May 2026
    Not My Lever

    The Last Container

  • 25 Apr 2026
    The Lightening of Intent

    Why Execution Got Cheap and Intent Got Live

Links out, with commentary.

  • 25 Jul 2026
    India's first privately developed rocket reaches orbit on dramatic debut launch arstechnica.com

    Bookmarked: https://arstechnica.com/space/2026/07/indias-first-privately-developed-rocket-reaches-orbit-on-dramatic-debut-launch/ Very cool for any team to get …

  • 24 Jul 2026
    Hadley Wickham on AI and its role in data science open.substack.com

    Bookmarked: https://open.substack.com/pub/tidydesign/p/y-code-when-ai The wonderful Hadley Wickham gives his overview on how and why to use AI in Data Science …

  • 25 Nov 2025
    much love to everybody

    xkcd published this wonderful piece: https://xkcd.com/3172/ want to feel old?

  • 4 Aug 2025
    Links 20250803

    Writing (almost) every day for the past month has been exhausting. It slowed down me reading significantly to say the least. But it proved a point to myself, …

  • 10 Jun 2025
    Carry you home

    Sometimes the algorithms find just the right thing. Carry you home is a beautiful song. Especially for those days and nights when parenting is a little bit of …

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