Aneesh Sathe
I work at the intersection of AI, data science, and biomedical R&D — mostly on systems that help scientists turn messy biological and clinical data into clearer decisions.
Currently VP of AI & Data Science at Qureator; before that I co-founded Qritive, an AI pathology company. I write with the Protocol Institute on World Machines.
This site is where I write about technology, books, leadership, music, family, startups, and whatever else I'm trying to understand.
Short notes and microblog posts.
Would we be really happy if it were an AI that we sent out into the universe and it made first contact with other intelligences? Would we count that as first contact? Certainly it’s difficult to think …
In the age of AI, evolutionary theory will become a critical cultural and business theory. This is because evolution is concerned with observed life. Life is essentially information that folds upon …
Contraptions Book Club # August book is Darwin’s Dangerous Idea — Evolution, and the Meanings of Life by Daniel C. Dennett Starting the August book, past 2 months have been software development and …
Had Chitale pedas after what feels like years. Is there a more perfect Indian sweet? I say not.
It is a strange happiness to really grasp the differences between the words prediction and anticipation. That there is a difference at all. When I sought to understand the difference I anticipated …
Longer, more developed essays.
- 21 Jul 2026On Thickets, Enclosure, and LeavingWorld Machines
Back to Liveness
8 min read - 19 Jul 2026The Birth of ThicketsWorld Machines
An Interregnum in Space
11 min read - 3 Jul 2026The Ocean
Wound up at the beach today. A proper San Diego beach. Unlike Carlsbad beaches, San Diego beaches tend to be a bit cropped but they are always livelier. This …
2 min read - 12 May 2026Not My LeverWorld Machines
The Last Container
12 min read - 25 Apr 2026The Lightening of IntentWorld Machines
Why Execution Got Cheap and Intent Got Live
16 min read
Essays in the World Machines collection.
Links out, with commentary.
- 27 Jul 2026Em dashes are fucking amazing psychotechnology.substack.com
Bookmarked: Em dashes are fucking amazing Working with AI helped me actually learn punctuation because clarity makes better prompts. Reading em-dashes in text …
- 25 Jul 2026You don’t have to blog like me danq.me
Bookmarked: You don’t have to blog like me Nice post. When exiting the platforms the habit of posting for internet points is strong. This is a reminder that you …
- 25 Jul 2026India's first privately developed rocket reaches orbit on dramatic debut launch arstechnica.com
Bookmarked: https://arstechnica.com/space/2026/07/indias-first-privately-developed-rocket-reaches-orbit-on-dramatic-debut-launch/ Very cool for any team to get …
- 24 Jul 2026Hadley Wickham on AI and its role in data science open.substack.com
Bookmarked: https://open.substack.com/pub/tidydesign/p/y-code-when-ai The wonderful Hadley Wickham gives his overview on how and why to use AI in Data Science …
- 25 Nov 2025much love to everybody
xkcd published this wonderful piece: https://xkcd.com/3172/ want to feel old?
