LinkBlog on Aneesh Sathe

Nicheverse

Sat, 08 Aug 2026 16:20:27 +0000

Bookmarked: Nicheverse

Bio research gets more interestinger every day, cool work here mapping niches and cell states

Carl’s Required Reading

Sat, 08 Aug 2026 14:49:13 +0000

Bookmarked: Carl’s Required Reading

Good set

Farewell to a famous parrot : Nature News

Sat, 08 Aug 2026 04:16:24 +0000

Bookmarked: Farewell to a famous parrot : Nature News

Unexpected feels 🦜

“You be good,” said Alex last Thursday night. “I love you. See you tomorrow.”

via Sven Dahlstrand

I’m in the park reading Claire L. Evans’ book Broad Band.. - Sven Dahlstrand

Sat, 08 Aug 2026 04:10:44 +0000

Bookmarked: I’m in the park reading Claire L. Evans’ book Broad Band.. - Sven Dahlstrand

Code and poetry ❤️

vgr: I have perfected my sev puri

Sat, 08 Aug 2026 01:20:11 +0000

Bookmarked: vgr: I have perfected my sev puri

When the chai is declared perfected I’m arriving unannounced

How to avoid the “clean data, clean model” trap when teaching statistics and data science

Sat, 08 Aug 2026 00:47:40 +0000

Bookmarked: How to avoid the “clean data, clean model” trap when teaching statistics and data science

Excellent thinking about teaching stats but also for data science leadership thinking about team training. It softens my usual throw in the deep end approach but I like it.

I Built a Blog and Forgot to Write - Ben's Web Space

Thu, 06 Aug 2026 07:52:06 +0000

Bookmarked: I Built a Blog and Forgot to Write - Ben’s Web Space

Glad I was lazy to begin with and made it easy to post to my blog…

Physicist say that they have found the origin of causality

Wed, 05 Aug 2026 06:34:42 +0000

Bookmarked: Physicist say that they have found the origin of causality)

This one is apparently not Quantum woo.

Pandoc - twenty-years-of-pandoc

Tue, 04 Aug 2026 00:26:27 +0000

Bookmarked: Pandoc - twenty-years-of-pandoc

Round of applause for the software keepers. Pandoc simplified so much and continues to be a robust and reliable tool for document wrangling.

Agent Harness Engineering vs. Loop Engineering vs. Graph Engineering

Sat, 01 Aug 2026 21:06:00 +0000

Bookmarked: Agent Harness Engineering vs. Loop Engineering vs. Graph Engineering

Coding Agents Don’t Need Bigger Context Windows — They Need a Context Compiler | Towards Data Science

Sat, 01 Aug 2026 21:00:25 +0000

Bookmarked: Coding Agents Don’t Need Bigger Context Windows — They Need a Context Compiler | Towards Data Science

Interesting way to not just reduce but actually control context. Should try it out. Wondering if this can be applied to text files also…

I ♥ RSS – Andrew Shell's Weblog

Sat, 01 Aug 2026 18:13:04 +0000

Bookmarked: I ♥ RSS – Andrew Shell’s Weblog

Everyday something fun around RSS.

Blaugust 2026 is Coming!

Sat, 01 Aug 2026 18:04:49 +0000

Bookmarked: Blaugust 2026 is Coming!

TIL Blaugust is a thing. Looks fun. also so many people writing and wanting to write

sudo boo

Sat, 01 Aug 2026 14:53:50 +0000

Bookmarked: sudo boo

Hehe always here for sudo jokes

On Turning Ten by Billy Collins

Fri, 31 Jul 2026 05:31:03 +0000

Bookmarked: On Turning Ten by Billy Collins

Such a beautiful poem this is, On Turning Ten by Billy Collins

I didn’t expect to see my younger self in it and yet there I was — thinking “This is the beginning of sadness”

Ontologies Are So Back: Why AI Agents Are Reviving the Semantic Web

Thu, 30 Jul 2026 15:07:06 +0000

Bookmarked: Ontologies Are So Back: Why AI Agents Are Reviving the Semantic Web

Bringing this to AI in bio-sciences will be critical for AI to be even more useful than it is now.

“In computer science, an ontology is “a description of data structure – of classes, properties, and relationships in a domain of knowledge” (as nicely defined by Oxford Semantic Technologies). Coyle himself defined an ontology as simply “data as graphs.” He added that ontologies as a concept go right back to Aristotle, and have been used throughout the history of Artificial Intelligence.“ And “ you can have a reasoner built on ontology, to check [and] keep the LLM on track — have guardrails to keep it honest”

The Last Museum

Thu, 30 Jul 2026 03:12:48 +0000

Bookmarked: The Last Museum

Search engine for museum art

About RSS.chat

Wed, 29 Jul 2026 15:02:08 +0000

Bookmarked: About RSS.chat

RSS.chat seems to be a wild entry back into the open web. Especially since Wordpress built a deep integration: When the walls came down

Is this…. Google Reader? 🦋

I don’t know… but exciting times.

Substack writers, you need a website!

Wed, 29 Jul 2026 04:28:56 +0000

Bookmarked: Substack writers, you need a website!

Every few years there are imploring shouts that people should have their websites. Unfortunately they lead to nothing, but I’m glad it happens, I’m sure it converts at least a few. Obviously, I agree. What is even more true now is that with some set up help from Al it is trivial and even free if you want to host your own website.

Em dashes are fucking amazing

Mon, 27 Jul 2026 01:17:06 +0000

Bookmarked: Em dashes are fucking amazing

Working with AI helped me actually learn punctuation because clarity makes better prompts. Reading em-dashes in text helped me understand em-dashes. Now I use them — alll the time.

You don’t have to blog like me

Sat, 25 Jul 2026 19:41:08 +0000

Bookmarked: You don’t have to blog like me

Nice post. When exiting the platforms the habit of posting for internet points is strong. This is a reminder that you can do your thing.

India's first privately developed rocket reaches orbit on dramatic debut launch

Sat, 25 Jul 2026 06:05:50 +0000

Bookmarked: https://arstechnica.com/space/2026/07/indias-first-privately-developed-rocket-reaches-orbit-on-dramatic-debut-launch/

Very cool for any team to get this right on the first try. Amazing work by the scientists and engineers.

Hadley Wickham on AI and its role in data science

Fri, 24 Jul 2026 22:17:33 +0000

Bookmarked: https://open.substack.com/pub/tidydesign/p/y-code-when-ai

The wonderful Hadley Wickham gives his overview on how and why to use AI in Data Science work. The conclusion is actually applicable to anyone using AI in their work: “AI is an amplifier. And I really urge you, to the best of your abilities, to use it to amplify the best parts of you, the most human parts of you — not the laziest part.”

Nothing Ventured

Thu, 10 Jul 2025 04:51:52 +0000

The wave towered over me. Then the sound filled my ears. Not the calm breath of the waves; but it was surf music. I was maybe 3. Song names and artist names were beyond me. There was only the blue-green wave and the twang of the guitar.

I have chased music all my life. Just had to figure out the tools. The record player and the giant speakers taught my first lesson: pressing buttons was joy. In my pursuit I learned in about records, tapes, CDs, mp3, flac, streaming, Napster, torrents, Winamp, VLC, blanks, CD-R/RWs, compression, bit rates, conversion, transfer, backups, VPN, networking, impedance matching, DACs, amplifiers, calibration, ARC, fibre, buying, licensing, and streaming in approximate order.

20250605 links

Fri, 06 Jun 2025 03:42:44 +0000

Causality Podcast #

Just discovered this it promises to be promising:

https://causalbanditspodcast.com/

AI deals show no signs of slowing #

https://www.nature.com/articles/d43747-025-00027-z

Collectively, four notable trends are emerging;

an increase in upfront commitments

specialization in new therapeutic modalities (such as biologics rather than small molecules)

the rise of niche dataset providers

increasing participation from mid-to large-cap biotechs that are following the early adopters.

Brain cells compute cluster #

https://spectrum.ieee.org/biological-computer-for-sale

On the rheology of cats

Fri, 24 Jan 2025 03:50:33 +0000

Probably the cutest paper you’ll read today.

The wetting and general tribology of cats has not progressed enough to give a definitive answer to the capillary
dependence of the feline relaxation time. Fig. 2b gives
an example of a lotus effect of Felis catus, suggesting
that the substrate is superfelidaphobic. […]
cats are proving to be a rich model system for rheological research, both in the linear and nonlinear regimes.

Untitled

Thu, 23 Jan 2025 06:32:28 +0000

It seems monstrosity requiresan organic element. When there isn’t one, monsteris more often an adjective than a noun qualifying an incomplete potentialfor monstrosity.

[…]

Monumentality embodies distant, impersonal forces at work, that pose a terrifying threat because they don’tcare about us. Monsters on the other hand, care enough to be deliberately threatening to us.

Includes a recipe for making the perfect monster! — Reading on contraptions.venkateshrao.com/p/monsters-and-mediocrity

Untitled

Mon, 20 Jan 2025 05:03:27 +0000

Every few years decentralization and RSS feeds come back into the ligh. Usually this happens when one otherwise functional social media site dies in a real or practical way. Google Reader being my, and my generation’s, touchstone.
During these times of turmoil, a beautiful soul puts together a guide for how to use RSS. This is a good guide for this iteration:

Escape the walled garden and algorithm black boxes with RSS feeds

Untitled

Mon, 20 Jan 2025 04:50:19 +0000

I’m taking part in the Contraptions Book Club where we are reading City of Fortune which is about Venice. I was struck by the character of Doge Dandolo. Dude was 80+ when we saw a trade opportunity in the 4th Crusades. In the book, the author, Roger Crowley describes a brief moment when Dandolo makes a heroic rush on the banks of Constantinople’s Golden Horn during the Sack of Constantinople.

I found both the Doge and the imagery interesting so went looking for art depicting the art, there’s supposed to be lots. Unfortunately I couldn’t find any and nothing in the public domain. So I asked AI to generate something.

Untitled

Sat, 18 Jan 2025 08:06:00 +0000

Came across a heartwarming fan-made comic of a collaborative story told on tumblr. A farmer makes a temple to see who shows up and it’s a self-doubting god of transient beauty. This immediately brought back the Small Gods from Discworld, but also the poem Worm by Gail Mcconnell.

The comic and the story are beautiful. Perhaps there is some sense to shrines…

The God of Arepo- PDF available

via metafilter

Untitled

Sat, 18 Jan 2025 07:09:14 +0000

Trying something different for a few days. Instead of spamming all the social media accounts with daily links, I will post links only on the blog everyday. Maybe even multiple times a day.

Still thinking about doing a weekly digest or something. Let’s see.

Jan 17, 2025

Fri, 17 Jan 2025 08:06:00 +0000

Table Turpentine #

Came across the gt package for better tables in R. Might sound silly but it’s one of those cheap turpentine things.

Who made the train? #

via ChiPa

Yunus Emre-The Watermill #

via harvard blogs

Translation

Why do you groan, O Watermill; For I’ve troubles, I groan
I fell in love with the Lord; For It do I groan
They found me on a mountain; My arms and wings they plucked
Saw me fit for a watermill; For I’ve troubles, I groan
From the mountain they cut my wood; My disparate order they ruined
But an unwearied poet I am; For I’ve troubles, I groan
I am The Troubled Watermill; My water flows, roaring and rumbling
Thus has God commanded; For I’ve troubles, I groan
I am but a mountain’s tree; Neither am I bitter, nor sweet
I am but a pleader to the Lord; For I’ve troubles, I groan
Yunus, whoever comes here will find no joy, will not reach his desire
Nobody stays in this fleeting abode; For I’ve troubles, I groan

Jan 16, 2025

Thu, 16 Jan 2025 08:06:00 +0000

Hardbreak: Hardware Hacking Wiki #

This was a cool little find. I’ve always played with software in one form or another, but besides building PCs actual hardware hacking felt out of reach. Maybe I can start with some simple things like radio hacking.

The beauty of understanding #

My love for science seems to always involve some sort of rube goldberg machine: you set things up just so and discoveries magically flow out. Sure, designing pretty experiments is difficult and there is a lot of literal and metaphorical heartbreak along the way but to finally discover the way is all frisson.

Jan 14, 2025

Tue, 14 Jan 2025 08:06:00 +0000

Font fight! #

The fonts have assembled, their ligatures sharp their curves are shiny. They all line up with perfect kerning… or do they? Your eyes and mind are their battlefield.

https://www.codingfont.com/

I got JetBrains mono btw.

Decentralization is just partial centralization #

Renée DiResta writes about the social media flux in Noema.

Decentralization places a heavy burden on individual instance administrators, mostly volunteers, who may lack the tools, time or capacity to address complex problems effectively.

Jan 13, 2025 Life, platforms, vectors

Mon, 13 Jan 2025 08:22:47 +0000

Crystal-Bison #

I don’t want to give away much of the poem but it captures the nature, ferocity, and purpose of life.

Ghost Exits #

Aligning with the idea that blogs will be the last of the [good internet](http://Jan. 3, 2025) there is a broader question about platforms and their methods. Long before meta and X abandoned all pretense the internet was already under attack while we were believed this was fine.

The Universal Library in the River of Noise

Sun, 12 Jan 2025 08:06:00 +0000

Few ideas capture the collective human imagination more powerfully than the notion of a “universal library”—a singular repository of all recorded knowledge. From the grandeur of the Library of Alexandria to modern digital initiatives, this concept has persisted as both a philosophical ideal and a practical challenge. Miroslav Kruk’s 1999 paper, “The Internet and the Revival of the Myth of the Universal Library,” revitalizes this conversation by highlighting the historical roots of the universal library myth and cautioning against uncritical technological utopianism. Today, as Wikipedia and Large Language Models (LLMs) like ChatGPT emerge as potential heirs to this legacy, Kruk’s insights—and broader reflections on language, noise, and the very nature of truth—resonate more than ever.

Jan 11, 2025 - Leading with Kindness

Sat, 11 Jan 2025 08:06:00 +0000

Leading with Kindness #

PDF kindly made available by the author, Steve Swensen - via Helen Bevan on Bluesky.

Steve Swensen held leadership positions at Mayo Clinic ensuring not just improving care but also preventing burnout. This paper from May 2024 provides leaders with a framework to help colleagues do better and “Kindness is helping people do better.”

That colleague or work environment that creates stress and anxiety have a very real impact on your health and long-term well-being. An organization can improve team health by creating space for “nurturing human conditions” to emerge:

Jan 10, 2025 - AI Agents, Machiavelli's Study

Fri, 10 Jan 2025 08:06:00 +0000

Agents Are Not Enough #

Last year I was heavily experimenting with Knowledge Graphs because it’s been clear that LLMs by themselves fall short because of the lack of knowledge. This paper by Chirag Shah and Ryen White (you can click the heading above) from Dec 2024 expands on those shortcomings by exploring not just knowledge but also value generation, personalization, and trust.

They open the paper by casting a very wide definition of an “agent” everything from thermostats to LLM tools. While this seems facetious at first, their next point is interesting. Agents by definition “remove agency from a user in order to do things on the user’s behalf and save them time and effort.”. I think this is an interesting way to injext an LLM flavored principal agent problem into the Agentic AI conversation.

Jan 9, 2025 - The Age of Fire and Gravel

Thu, 09 Jan 2025 08:05:00 +0000

Today I discovered the Public Domain Image Archive attached to the Public Domain Review which has some great essays and commentary on image collections, like the one below.

Utagawa Hiroshige: Last Great Master of Ukiyo-e #

Just before Hiroshige died, possibly of cholera, he wrote the following poem:

I leave my brush in the East
And set forth on my journey.
I shall see the famous places in the Western Land.

This was a fortelling of sorts because Hiroshige

Jan. 8, 2025: Count your DIGITS! Drunk Bayesian

Wed, 08 Jan 2025 08:06:00 +0000

NVIDIA Project DIGITS #

Around 2015 I was putting together funds in academia. Convincing IT, senior professors, and finance that yes, it was worth giving me a LOT of cash to build a workstation with multiple GPUs.

…
“No, it isn’t for gaming.”
…
“Yes, it will change the world.”
…
“No, there are no university rules that hardware bought multiple invoices across multiple departments can’t be used in the same box.”
…
“Yes, I’m aware that all my individual quotes are just below the bureaucracy summoning purchase limits.”
…
“Yes I tried random forest with the other stats and ML methods, this really is better. How do I know? Well…”

Jan. 7, 2025: Building Dwelling Thinking

Tue, 07 Jan 2025 14:00:00 +0000

Today’s product builders and data scientists shape the way people see the world. The analysis, plots, and UI we create are places where others dwell. Not merely occupy but live and harness the mental space we give them access to. Martin Heiddeger wrote Building Dwelling Thinking(archive.org) in his 1971 book, Poetry Language Thought.

Man’s relation to locations, and through locations to spaces, inheres in his dwelling. The relationship between man and space is none other than dwelling, strictly thought and spoken

Jan. 6, 2025

Mon, 06 Jan 2025 14:00:00 +0000

VMC: A Grammar for Visualizing Statistical Model Checks #

Data Scientists check how well a statistical model fits observed data with numerical and graphical checks. Graphical checks have a huge range outside of the well knowns like Q-Q plots. Scientists are of course limited by their training and experience, and it’s not trivial to arrive at effective model checks. Both programmatic and visual plotting tools require significant effort to generate new plots increasing the friction to do proper checks.
Work out of Jessican Hullman’s lab has created the VMC package (github) is a tool to easily access these methods and determine the quality of your model quickly. VMC is

Jan. 5, 2025

Sun, 05 Jan 2025 14:00:00 +0000

Improving Research Through Safer Learning from Data #

Another one of Frank Harrell’s posts. Given my day job, and the R&D background this one is quite close to home. As a team leader on the industry side one hopes to build a culture with the team that aligns scientific rigor with company goals. Any method, statistical or cultural (in this case both), that solves for this tension will get you the most bang for your buck.

Jan. 3, 2025

Fri, 03 Jan 2025 17:07:56 +0000

In 2025, blogs will be the last bastion of the Good Internet #

Erik Hoel writes

a work of maximalism succeeds when it triggers this property in the experiencer. You know that the whole is there, but you can’t see it all at once. You can only take it in sequentially. It is the awareness of an emergent form you, as a limited being with only a periscope for perception, cannot actually understand in full.

2025-01-02 Links

Thu, 02 Jan 2025 11:43:50 +0000

Are we slowly entering the post data annotation world? #

The act of annotating data for ML has always been a shortcut to access concepts not present in the training data. This new work, incorporates literature with data to achieve a fuller picture with complementary information.

Specifically the tech,

utilizes GPT-4 to induce reliable disease-specific human expert concepts from medical literature and incorporate them with a group of purely learnable concepts to extract complementary knowledge from training data.

2025-01-01 Links

Thu, 02 Jan 2025 06:24:06 +0000

Beauty as resistance - Good visualization design is an act of liberation by Alberto Cairo

Good visualization tells the reader what the collected data is saying it creates a little place in an otherwise confusing space.

Truth and liberty are entwined in a self-reinforcing loop. When we design a good visualization we aren’t just conveying our best understanding of a truth; by sharing our contemplation of that truth, we’re also making ourselves and our readers freer.